Markus F Neurath Selected Research

Colitis

12/2022	PU.1-driven Th9 Cells Promote Colorectal Cancer in Experimental Colitis Models Through Il-6 Effects in Intestinal Epithelial Cells.
12/2022	Neutrophils prevent rectal bleeding in ulcerative colitis by peptidyl-arginine deiminase-4-dependent immunothrombosis.
11/2022	Label-Free Characterization and Quantification of Mucosal Inflammation in Common Murine Colitis Models With Multiphoton Imaging.
3/2022	Targeting STAT3 Signaling in COL1+ Fibroblasts Controls Colitis-Associated Cancer in Mice.
2/2022	Expression of inflammatory mediators in biofilm samples and clinical association in inflammatory bowel disease patients-a preliminary study.
10/2021	Targeting of the Tec Kinase ITK Drives Resolution of T Cell-Mediated Colitis and Emerges as Potential Therapeutic Option in Ulcerative Colitis.
1/2021	Dynamic, Transient, and Robust Increase in the Innervation of the Inflamed Mucosa in Inflammatory Bowel Diseases.
1/2021	E-type prostanoid receptor 4 drives resolution of intestinal inflammation by blocking epithelial necroptosis.
5/2020	The TLR9 Agonist Cobitolimod Induces IL10-Producing Wound Healing Macrophages and Regulatory T Cells in Ulcerative Colitis.
2/2020	Extent of Mucosal Inflammation in Ulcerative Colitis Influences the Clinical Remission Induced by Vedolizumab.

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Markus F Neurath Research Topics

Disease

103	Inflammation (Inflammations) 05/2022 - 07/2003
88	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 11/2022 - 07/2003
79	Neoplasms (Cancer) 12/2022 - 04/2003
78	Crohn Disease (Crohn's Disease) 01/2022 - 01/2002
77	Colitis 12/2022 - 01/2002
60	Ulcerative Colitis 12/2022 - 04/2003
30	Colorectal Neoplasms (Colorectal Cancer) 12/2022 - 09/2004
14	Infections 01/2022 - 04/2005
13	Necrosis 05/2022 - 01/2009
12	COVID-19 01/2022 - 01/2020
11	Fibrosis (Cirrhosis) 01/2022 - 08/2013
11	Colonic Neoplasms (Colon Cancer) 01/2020 - 04/2003
10	Colitis-Associated Neoplasms 01/2020 - 09/2008
9	Hemorrhage 12/2022 - 01/2012
9	Asthma (Bronchial Asthma) 01/2016 - 01/2002
8	Carcinogenesis 01/2016 - 09/2008
7	Autoimmune Diseases (Autoimmune Disease) 01/2020 - 12/2002
6	Arthritis (Polyarthritis) 06/2022 - 09/2006
6	Gastrointestinal Diseases (Functional Gastrointestinal Disorders) 10/2021 - 11/2006
6	Pathologic Constriction (Stenosis) 01/2019 - 01/2005
6	Rheumatoid Arthritis 11/2018 - 03/2007
5	Hepatitis 01/2021 - 01/2007
5	Graft vs Host Disease (Graft-Versus-Host Disease) 11/2019 - 08/2009
5	Polyps 01/2018 - 03/2014
4	Neoplasm Metastasis (Metastasis) 04/2022 - 05/2011
4	Lung Neoplasms (Lung Cancer) 01/2022 - 12/2012
4	Dysbiosis 10/2021 - 09/2018
4	Hepatocellular Carcinoma (Hepatoma) 03/2021 - 09/2012
4	Liver Diseases (Liver Disease) 01/2021 - 01/2008
4	Pruritus (Itching) 01/2021 - 11/2020
4	Psoriasis (Pustulosis Palmaris et Plantaris) 01/2021 - 12/2014
4	Disease Progression 12/2019 - 11/2002
4	Pneumonia (Pneumonitis) 01/2019 - 08/2008
4	Adenocarcinoma 08/2017 - 04/2009
4	Hypersensitivity (Allergy) 12/2015 - 02/2002
4	Respiratory Hypersensitivity 01/2014 - 06/2007
4	Barrett Esophagus (Barrett's Esophagus) 10/2013 - 01/2004

Drug/Important Bio-Agent (IBA)

74	CytokinesIBA 02/2022 - 01/2002
30	Interleukin-6 (Interleukin 6)IBA 12/2022 - 01/2003
23	Proteins (Proteins, Gene)FDA Link 04/2020 - 09/2003
22	AntibodiesIBA 01/2022 - 06/2007
20	Transcription Factors (Transcription Factor)IBA 01/2020 - 01/2002
17	OxazoloneIBA 11/2022 - 02/2002
16	InterleukinsIBA 02/2022 - 01/2006
15	vedolizumabIBA 11/2022 - 01/2017
15	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2022 - 11/2002
15	Interleukin-23 (Interleukin 23)IBA 01/2019 - 09/2003
13	IntegrinsIBA 11/2022 - 01/2017
13	Biological ProductsIBA 01/2022 - 08/2006
12	sodium sulfate (sodium bisulfate)FDA LinkGeneric 12/2022 - 01/2007
12	Interleukin-12 (IL 12)IBA 01/2020 - 11/2004
11	Dextrans (Dextran)FDA Link 01/2021 - 01/2007
10	Infliximab (Remicade)FDA Link 01/2021 - 01/2005
10	Azathioprine (Imuran)FDA LinkGeneric 04/2018 - 04/2003
9	Interleukin-9 (Interleukin 9)IBA 12/2022 - 07/2014
9	Interleukin-17 (Interleukin 17)IBA 01/2020 - 03/2007
9	Messenger RNA (mRNA)IBA 10/2017 - 01/2002
8	Dextran SulfateIBA 11/2022 - 12/2004
8	Interleukin-13IBA 01/2021 - 08/2008
8	Transforming Growth Factor beta (TGF-beta)IBA 07/2014 - 10/2004
7	Monoclonal AntibodiesIBA 11/2022 - 02/2003
7	Caspase 8 (Caspase-8)IBA 01/2022 - 09/2011
7	Coloring Agents (Dyes)IBA 01/2021 - 01/2004
7	LigandsIBA 01/2021 - 01/2008
7	Interleukin-27 (Interleukin 27)IBA 11/2011 - 04/2005
6	CollagenIBA 06/2022 - 04/2012
6	Pharmaceutical PreparationsIBA 01/2021 - 09/2008
6	DNA (Deoxyribonucleic Acid)IBA 01/2021 - 09/2012
6	Interleukin-4 (Interleukin 4)IBA 01/2020 - 02/2004
6	SteroidsIBA 01/2020 - 09/2006
6	AntigensIBA 05/2018 - 07/2003
6	Sulfonic AcidsIBA 07/2017 - 12/2002
5	tofacitinibIBA 04/2022 - 10/2017
5	Biomarkers (Surrogate Marker)IBA 04/2022 - 01/2012
5	Ustekinumab (CNTO 1275)FDA Link 10/2021 - 02/2019
5	AzoxymethaneIBA 01/2021 - 04/2010
5	Immunoglobulin E (IgE)IBA 01/2021 - 06/2011
5	Phenobarbital (Luminal)FDA Link 05/2020 - 07/2003
5	Indicators and Reagents (Reagents)IBA 07/2017 - 01/2007
5	Capsules (Microcapsules)IBA 09/2014 - 01/2012
4	Immunoglobulin G (IgG)IBA 01/2022 - 12/2020
4	Interleukin-10 (Interleukin 10)IBA 01/2022 - 11/2007
4	Adrenal Cortex Hormones (Corticosteroids)IBA 10/2021 - 05/2011
4	Immunosuppressive Agents (Immunosuppressants)IBA 10/2021 - 04/2003
4	InterferonsIBA 04/2021 - 02/2004
4	EnzymesIBA 01/2021 - 02/2016
4	Phosphotransferases (Kinase)IBA 01/2021 - 11/2016
4	Interleukin-5 (Interleukin 5)IBA 01/2020 - 01/2012
4	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 07/2015 - 08/2010
4	Fluorescein (Funduscein)FDA LinkGeneric 05/2015 - 01/2011
4	AllergensIBA 09/2014 - 01/2002
4	NeuropeptidesIBA 03/2012 - 04/2011
4	Calcitonin Gene-Related PeptideIBA 03/2012 - 04/2011

Therapy/Procedure

108	Therapeutics 12/2022 - 01/2003
31	Lasers (Laser) 06/2022 - 09/2004
7	Biological Therapy 10/2021 - 01/2009
6	Drug Therapy (Chemotherapy) 04/2020 - 12/2010
5	Precision Medicine 01/2019 - 03/2014
5	Surgical Instruments (Clip) 06/2018 - 07/2011
4	Palliative Care (Palliative Therapy) 01/2022 - 08/2013